CIAG Faculty help build research capacity and scientific prestige in
Integrated Animal Genomics through interdisciplinary collaborative research and
support of Center activities. To become affiliated with or learn more
about CIAG, or to update your information in the CIAG directory, please send an
email to ciag@iastate.edu.
|
NAME |
DEPARTMENT |
RESEARCH INTERESTS |
|
Adams, Dean C. |
Ecology, Evolution, and Organismal Biology;
Statistics |
Evolutionary ecology, and understanding
the evolution of complex phenotypes. Components of my empirical
work touch upon adaptive diversitification, phenotypic plasticity, and
quantitative genetics, largely in Plethodon salamanders. My
theoretical work involves the development of statistical and analytical
procedure for quantifying patterns of change in multivariate data |
|
Anantharam, Vellareddy |
Biomedical Sciences |
Cellular and molecular mechanism of neurodegeneration and
neuroprotection; development of novel strategies for treating
neurological disorders |
|
Bannantine, John |
National Animal Disease Center (USDA-ARS) |
Sequencing and analysis of the Mycobacterium avium
subspecies paratuberculosis genome |
|
Bartholomay, Lyric |
Entomology |
Employ microarrays and bioinformatics tools to describe
the molecular response within a mosquito that is triggered by infection
with a pathogen, emphasizing on arthropod-borne viruses (arboviruses) |
|
Baum, Thomas |
Plant Pathology |
Compatible interaction between cyst nematodes and their
hosts with particular emphasis on the soybean cyst nematode |
|
Beetham, Jeffrey |
Veterinary Pathology;
Entomology |
Parasitology, oxidative stress, lysozomes; gene
regulation |
|
Beitz, Donald C. |
Animal Science;
Biochemistry, Biophysics and Molecular
Biology |
Lipid metabolism; cholesterol homeostasis in animal and
humans; nutritional and genetic control of animal-derived food quality |
|
Berger, P. Jeffrey |
Animal Science |
High performance scientific computing procedures that
contribute to the genetic enhancement of livestock; genetic evaluation
of animals; parameter estimation, prediction of breeding values and
analysis of data sets that service the livestock industry |
|
Birt, Diane |
Food Science and Human Nutrition |
Identification and study of mechanisms for cancer
prevention by novel dietary constituents and mechanisms for cancer
enhancement by overeating and obesity; assessment of potential bioative
and toxic components of botanical dietary supplements and studies on the
mechanism of these effects |
|
Blitvich, Brad |
Veterinary Microbiology and Preventive Medicine |
Arthropod-borne viruses (arboviruses); molecular
determinants of arbovirus-vector interactions; sequencing and
characterization of genes involved in apoptotic regulation in mosquito
vectors; epidemic potential of West Nile virus in Mexico |
|
Blanchong, Julie |
Natural Resource Ecology and Management |
Wildlife disease ecology and genetics; use of molecular
genetic techniques to identify and characterize susceptibility, routes
of transmission, spatial distribution, and impacts of disease in
wildlife populations |
|
Bonning, Bryony |
Entomology |
Virus pathogenesis; molecular determinants of baculovirus
host range; virus-based strategies for management of insect pests and
plant disease |
|
Bronikowski, Anne |
Ecology, Evolution, and Organismal Biology |
Evolution of life history variation with empahsis on
senescence studied through field and laboratory experiments
(physiological and molecular genetic) and mathematical/computational
modeling |
|
Carriquiry, Alicia |
Statistics |
Nutrition and dietary assessment; Bayesian methods and
applications; environmental statistics |
|
Chou, Hui-Hsien |
Genetics, Development, and Cell Biology;
Computer Science |
Modeling of self-replication behaviors using cellular
automata; computational biology |
|
Coffman, Clark R. |
Genetics, Development, and Cell Biology |
Developmental genetic analyses of the networks mediating
cell migration and programmed cell death using Drosophila germ cells as
a model system for metastasis |
|
Cook, Dianne |
Statistics |
Dynamic graphics; exploratory data analysis; multivariate
methods; statistical computing |
|
Cornick, Nancy |
Veterinary Microbiology and Preventive Medicine |
Bacterial colonization mechanisms; zoonotic transmission
of bacterial pathogens; microbial ecology of gastrointestinal systems |
|
Day, Tim |
Biomedical Sciences |
Neuromuscular systems of parasitic worms; bioinformatic
and PCR-based efforts to discover neuropeptide receptors in parasitic
worms |
|
Dekkers, Jack C. M. |
Animal Science |
Quantitative genetics and animal breeding with
application to swine genetics, including design and optimization of
breeding strategies, use of molecular genetic information, QTL
detection, and economic aspects of breeding programs |
|
Dickerson, Julie |
Electrical and Computer Engineering |
Intelligent systems; bioinformatics; pattern recognition;
data visualization |
|
Dobbs, Drena |
Genetics, Development, and Cell Biology |
Protein structure prediction; algorithms for genome-wide
identification of protein structural homologs, discovery of sequence and
structural correlates of protein-ligand recognition |
|
Dorman, Karin |
Statistics;
Genetics, Development, and Cell Biology |
Biomathematics, computational biology, stochastic
modeling, bioinformatics; models of viruses and phylogenetic trees |
|
Ellinwood, Matthew |
Animal Science |
Pathogenesis and therapy of canine and feline models of
lysosomal storage disorders, neurodegeneration associated with lysosomal
accumulation of haparan sulfate and GM1 and GM2 gangliosides,
identification of novel feline and canine models of human disease |
|
Essner, Jeffrey J. |
Genetics, Development, and Cell Biology |
Genomics approach using zebrafish to model migration of
and formation of blood supply for cancer cells and identify genes that
are required at specific steps in cancer progression |
|
Eulenstein, Oliver |
Computer Science |
Algorithms, computational complexity, bioinformatics,
computational biology; design of algorithms to construct large subtrees
of the "Tree of life; the inverse protein folding problem |
|
Fernando, Rohan |
Animal Science |
Statistical methodology for mapping QTL; marker assisted
selection; genetic evaluation and parameter estimation in crossbred
populations |
|
Garrick, Dorian |
Animal Science |
Interested in genetics and its application to the
improvement of animal populations |
|
Girton, Jack |
Biochemistry, Biophysics and Molecular Biology |
Developmental and molecular genetics pf Drosophilia
pattern formation, genetic regulation of cell determination |
|
Greenlee, Heather West |
Biomedical Sciences |
Characterization of photoreceptor differentiation using
proteomics and the role IGF-1 signaling plays in this process; use of
retinal anatomy to better understand transmissible spongiform
encephalopathy pathogenesis |
|
Gu, Xun |
Genetics, Development, and Cell Biology |
Evolutionary functional genomics; comparative and
evolutionary genomics; multi-layer genome data exploration and gene
network evolution; human population genetics and primate evolution |
|
Harris, D. L. Hank |
Animal Science |
Infectious diseases of swine and shrimp; new alternatives
to antimicrobials, specifically those that may reduce the levels of
human foodborne Salmonella in swine, pathogenic microbiology,
bacteriophage therapy, vaccinology, infectious agent elimination
techniques and xenotransplantation |
|
Hendrich, Suzanne |
Food Science and Human Nutrition |
Food toxicology; gut microbial metabolism of
phytochemicals; health effects and bioavailability of soybean isoflavine,
detoxification of fumonisin (a corn fungal toxin), immune and other
cellular functional regulation by prostaglandins and oxidatively
modified (S-thiolated) proteins |
|
Honavar, Vasant |
Computer Science |
Artificial intelligence, bioinformatics and computational
biology; biological computation; cognitive science; data mining and
knowledge; discovery, distributed information systems; intelligent
agents and multi-agent systems; knowledge representation and inference;
machine learning and computational learning theory; complex systems
monitoring and control |
|
Huiatt, Ted |
Animal Science;
Biochemistry Biophysics and Molecular
Biology |
Regulation of embryonic skeletal muscle growth and
differentiation; assembly of myofibrillar proteins during embryonic
development of skeletal muscle |
|
Janzen, Fredric |
Ecology, Evolution, and Organismal Biology |
Biology of reptiles, including population genetic
structure and molecular evolution; evolutionary physiology;
computational biology; evolutionary ecology; conservation biology;
life-history evolution; computer modeling of hybrid zones and population
demography |
|
Jernigan, Robert |
Baker Center for Bioinformatics and Biological Sciences;
Biochemistry, Biophysics, and Molecular Biology |
Molecular computational biology (computational studies on
the structures of proteins, nucleic acids, and small molecules, and
their interactions); functions of large structures (relationship between
structures and sequences; protein threading, protein interactions with
other biomolecules, conformation generation, large domain motions of
protein and assemblages, including the ribosome, and systems biology) |
|
Jones, Doug |
Veterinary Pathology |
Host factors that influence the development of resistance
and susceptibility to infectious diseases caused by intracellular
pathogens, murine immune response to the protozoal parasite Leishmania
and the bovine immune response to Mycobacterium avium subs
paratuberculosis |
|
Kanthasamy, Arthi |
Biomedical Sciences |
The overall long term goal of my lab is to identify
cellular mechanisms underlying region specific neuronal vulnerability in
neurodegenerative conditions including ischemia, Parkinsons' disease and
methamphetamine-induced neurotoxicity |
|
Kline, Karen |
Veterinary Clinical Sciences |
Working in collaboration with Dr. Matthew Ellinwood on
the Neurologic manifestations of MPS1 and MPS3 in the canine with
emphasis on therapeutic modalities and quantification of neurologic
examination abnormalities. |
|
Lamont, Susan |
Animal Science |
Molecular genetics and immunogenetics of poultry;
identification of molecular markers and genes controlling bacterial
resistance, antibody kinetics, growth, body composition, skeletal
integrity and other biological traits; physiological genetics; gene
expression; major histocompatibility complex genes |
|
Lavrov, Dennis |
Ecology, Evolution, and Organismal Biology |
Molecular evolution, phylogenetics, and comparative
genomics; use of gene order data for the analysis of ancient
relationships; evolution of animal mitochondrial DNA with a special
emphasis on arthopods and sponges; bioinformatics |
|
Levine, Howard |
Mathematics |
Mathematical biology; applied mathematics and
mathematical modeling; partial differential equations |
|
Liu, Peng |
Statistics |
Statistical genetics, bioinformatics, inference for
high-dimensional data such as microarray |
|
Lonergan, Elisabeth Huff |
Animal Science |
Post-mortem conversion of meat and muscle biology
|
|
Lonergan, Steven |
Animal Science |
Mechanisms governing degradation of skeletal muscle
protein |
|
Mabry, John |
Animal Science |
Across herd genetic evaluation; genetic parameter
estimation; genetic system design and implementation; application of
BLUP breeding value estimation for on-farm usage; integration of
molecular genetics with quantitative genetics for profitable swine
production |
|
Mallapragada, Surya |
Chemical and
Biological Engineering |
Bioinspired smart copolymers; patterned surfaces for
nerve regeneration; combinatorial synthesis and characterization of
polyanhydrides; semicrystalline polymer drying |
|
Mayfield, John |
Genetics, Development, and Cell Biology |
Evolution and computation; general physical and
mathematical principles regarding biological evolution |
|
McGrail, Maura A. |
Genetics, Development, and Cell Biology |
Molecular genetics in the vertebrate model organism
zebrafish; transgenic approaches to model cancer; development of gene
targeting methods for functional genomic studies |
|
McLellan, Gillian J. |
Veterinary Clinical Sciences |
Clinical and genetic characterization of inherited
glaucoma using an established colony of Siamese cats with this disease,
and the development of this animal model as a resource for glaucoma
research |
|
Miller, Cathy |
Veterinary Microbiology and Preventive Medicine |
Viral molecular biology, including understanding the
regulation of viral translation and replication in the context of the
host cell and its varied defenses. |
|
Minion, Chris |
Veterinary Microbiology and Preventive Medicine |
Molecular mechanisms of microbial pathogenesis;
pathogenomics; proteomics; gene expression profiling and molecular
vaccines |
|
Morrison, Jo Ann |
Veterinary Clinical Sciences;
Veterinary Teaching
Hospital |
Areas of interest include canine and feline thyroid
disease and hepatitis in Doberman pinschers. |
|
Narasimhan, Balaji |
Chemical and
Biological Engineering |
Molecular design of polymer interfaces;
structure-property relationships in lithographic polymers; bioerodible
polymers with tailored microstructure for controlled drug/vaccine
delivery; rational protein stabilization strategies using nanostructured
biodegradable block copolymers; combinatorial strategies for nanoscale
design and testing of adhesives and nanocomposites |
|
Nettleton, Dan |
Statistics |
Order restricted inference; mapping of quantitative trait
loci (QTL); categorical data analysis |
|
Nilsen-Hamilton, Marit |
Biochemistry, Biophysics, and Molecular Biology |
Regulation of gene expression by growth factors in animal
cells; tissue-specific regulation of gene expression; imaging gene
expression; interaction between mother and fetus during reproduction
|
|
Nolan, Lisa |
Veterinary Microbiology and Preventive Medicine |
Bacterial diseases of production animals, including their
effects on animal health, public health and food safety; molecular basis
of virulence and antimicrobial resistance of avian pathogenic
Escherichia coli (APEC) and other E. coli and Salmonella spp. causing
disease in various host species |
|
Phillips, Greg |
Veterinary Microbiology and Preventive Medicine |
Bacterial genetics and molecular biology of membrane
protein localization; structure and functional analysis of the signal
recognition particle; genetic tools for study of gene function
|
|
Powell-Coffman, Jo Anne |
Genetics, Development, and Cell Biology |
Genetic analysis of hypoxia response and aryl hydrocarbon
receptor signaling, using C. elegans as a model system
|
|
Proulx, Stephen |
Ecology, Evolution, and Organismal Biology |
Use of mathematical tools to study a variety of problems
in evolutionary ecology, including genetic networks, gene families,
mating systems, sex allocation, host-pathogen interactions, and niche
breadth |
|
Reecy, James |
Animal Science |
Transcriptional control of skeletal muscle growth and
development; molecular mechanisms controlling heart formation; beef
cattle molecular genetics; bovine microarray |
|
Reilly, Peter |
Chemical and
Biological Engineering |
Production, crystallization, and structural
characterization of primitive glucoamylases; production,
crystallization, and structural characterization of bacterial cellulases;
computational analysis of hydrolase and carbohydrate-binding protein
mechanisms; determination of compositions of agricultural and food
processing residues |
|
Reinhardt, Tim |
National Animal Disease Center (USDA-ARS); Animal Science |
Cellular and molecular mechanisms regulating calcium
transport in the mammary gland; the role of mammary calcium transport in
the development of clinical and subclinical hypocalcemia in dairy cows;
proteomic analysis of the mammary gland in different developmental
states |
|
Richt, Juergen |
National Animal Disease Center (USDA-ARS);
Veterinary
Microbiology and Preventive Medicine |
Pathogenesis of viral and diseases; reverse genetics;
molecular diagnostics; animal protection from infectious diseases;
microbial virulence; vaccines; virology |
|
Robson, Rich |
Animal Science;
Biochemistry, Biophysics, and Molecular
Biology |
Biochemistry, molecular biology, structure and function
of contractile and cytoskeletal proteins in muscle cells |
|
Rosenbusch, Ricardo |
Veterinary Microbiology and Preventive Medicine |
Molecular events in mycoplasmal and bacterial infection
of ruminants, emphasizing bovine respiratory disease and pinkeye;
virulence attributes of ruminant mycoplasmas; diagnostic systems for
mycoplasma infections; characterization of surface markers on equine
tenocytes |
|
Rothschild, Max |
Animal Science |
Gene mapping; identification of genes controlling growth,
reproduction and immunogenetics of swine; new statistical methods to
evaluate animals |
|
Sakaguchi, Don |
Genetics, Development, and Cell Biology |
Developmental neurobiology, stem cell transplantation,
development and regeneration of vertebrate visual systems, glaucoma and
other retinal diseases, coupled biological and mathematical modeling of
neural stem cell pattern formation |
|
Schalinske, Kevin |
Food Science and Human Nutrition |
Nutritional and hormonal regulation of folate/methyl
group metabolism relevant to health and disease |
|
Serb, Jeanne M. |
Ecology, Evolution, and Organismal Biology |
Molecular evolution; evolution of developmental pathways;
identification of genetic and environmental factors involved in complex
trait evolution, with an emphasis on eyes; phylogenetics |
|
Singh, Ravindra |
Biomedical Sciences |
Interested in identifying the genome-wide distribution of
novel cis-elements that regulate alternative splicing in humans and
animals |
|
Sponseller, Brett |
Veterinary Microbiology and Preventive Medicine;
Veterinary Clinical Sciences |
Equine viral pathogens; equine immune responses
|
|
Spurlock, Diane Moody |
Animal Science |
Identification of genes influencing energy balance in
dairy cattle; QTL identification; analysis of gene expression;
Investigation of functions of novel genes |
|
Spurlock, Michael E. |
Food Science and Human Nutrition;
Animal Science |
The role of adipocytes and inflammation in obesity and
insulin resistance; specifically, the role of the adipocyte-derived
hormone, adiponectin, in the regulation of energy metabolism and
pro-inflammatory cytokine production in peripheral tissues and the
immune system, and how these integrated regulatory pathways influence
obesity and its co-morbidities |
|
Stalder, Ken |
Animal Science |
Swine genetics and management; genetic and management
effects on pork quality; swine waste and nutrient management; management
to improve reproductive efficiency of sows; management of
growing-finishing swine to improve profitability |
|
Tuggle, Christopher |
Animal Science |
Gene expression; gene transfer; genome mapping and
analysis; embryogenomics; genome structure and function |
|
Valenzuela, Nicole |
Ecology, Evolution, and Organismal Biology |
Gene discovery, comparative gene expression; chromosome
evolution; microsatellites DNA; mitochondrial DNA; population structure;
ecological and conservation genetics |
|
Wang, Kan |
Agronomy |
Genetic transformation of corn, soybean and rice;
development of plant-based edible vaccines |
|
Wang, Zhengdao |
Electrical and
Computer Engineering |
Information and communication theory; Genomic
signal processing |
|
Wannemuehler, Michael |
Veterinary Microbiology and Preventive Medicine |
Interactions between host and bacterial pathogens with
regards to mucosal immunity and inflammatory diseases of the bowel; role
normal flora has on development of mucosal immunity and mechanisms of
antigen-specific T cell responses to regulate inflammation |
|
Wendel, Jonathan |
Ecology, Evolution, and Organismal Biology |
Molecular evolution, genome evolution, and phylogenetics
of higher plants; use of molecular and genetic tools to explore
evolutionary change in DNA sequences and relationships with
morphological change; analysis of polyploidy, with a special focus on
the cotton genus |
|
White, Wendy |
Food Science and Human Nutrition |
Nutritional genomics; bioavailability and metabolism of
carotenoids, including beta-carotene and lutein; health protective
effects of carotenoids; use of stable isotopic tracers to measure the
bioefficacy of beta-carotene in humans; molecular biology and
nutritional modulation of beta-carotene 15,15'-monooxygenase activity;
biofortification to combat vitamin A malnutrition |
|
Zhang, Qijing |
Veterinary Microbiology and Preventive Medicine |
Molecular and genetic basis of bacterial adaptation,
mechanisms of antimicrobial resistance and persistence,
transformation-mediated horizontal transfer of genetic materials, and
development of control measures for foodborne diseases |